Now I want Matt Damon as special guest

This guy is a savage!

Jimmy needs to get Keanu Reeves as special guest

Don’t done let you froget that Lil Moosey woke up like da man.

“Anne Perkins”

‘Twas fun, fun, fun all the way! Thanks so much to the “Jimmy Kimmel Live!” team for putting together such a fun show and thanks, Rob (Lowe), for being such a hilarious guest host, and last but not least, for making me a part of the show! It was delightful and exciting! Enjoyed chatting with the other participants! Thank you all, and all the best!

hey mr rob lowe you would be great as uncle jessie’s brother in full house or fuller house

I knew both right off!! Yes I’m a patient but high is not the feeling anymore pain management. Its a gift that devils 😈 🤪 lettuce ! Haaaaaaa

Did you know that Rob Lowe and Stephen Colbert were born in the same year? (fun fact)

So nice to hear someone who made it through quarantine on the wagon. I began quarantine around 6 months sober and watched everyone drink, and “connect”, even TV hosts and their guests, because that’s how everyone seemed to be staying united. Gotta admit I felt left out and alone. But I just celebrated my year sobriety and feel stronger because of it. Again, nice to see others out there too that are weathering the storm sober.

chris traeger would only approve if it was medical cbd

Me. Obviously.

I thought it was 86′

“”””””Love for Jane.””””””💚💚💚💜💜💜💜💤💤💤💤💤

His eyes, wtf! Even on the worst phone, worst resolution, i can still see his fukin blue eyes!

If you want real funny show invite little mix

I guessed right

Rob freakin Lowe…. Hell YEAHHH

This was entertaining “Getting Rob Lowe to guess who is high”

The future of Zac Efron